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Description
Master nutrition science and biochemistry through clinical reasoning - not recall. Built for the June 2026 USMLE nutrition update.
Kinetics is designed for medical students preparing for Step 1, Step 2 CK, and Step 3, built around the 2026 USMLE update that broadened nutrition biochemistry and chronic-disease testing across all three Step exams. Every case and pathway is mapped to the JAMA 2024 nutrition-competency framework that the USMLE cites as its alignment standard.
WHO IT'S FOR
‣ Medical students preparing for USMLE Step 1, Step 2 CK, and Step 3
‣ M1/M2 students in biochemistry and nutrition courses
‣ International medical graduates (IMGs) preparing for US licensure
‣ Residents reviewing nutrition for in-training exams or board recertification
‣ PA, NP, and pharmacy students mastering nutrition mechanisms
THE THREE-PILLAR LOOP
Every session follows the same flow:
‣ CASE - Open a patient vignette. Review the history. Order relevant labs at a cost - targeted workups earn more. Commit to a differential diagnosis.
‣ PATHWAY - Once you nail the DDx, map the biochemistry. Drag substrate, enzyme, cofactor, and product into a mechanism chain that explains why the clinical picture emerged. Understanding builds as you build.
‣ SPACED REPETITION - Missed a pathway? It returns tomorrow. Nailed it? It advances to 3, 7, or 21 days. Your knowledge stays durable between now and test day.
CONTENT
‣ 22 topic anchors: 13 vitamins, 6 minerals, and 3 macronutrient pathways - carbohydrate, fatty-acid, and amino-acid metabolism (urea-cycle nitrogen disposal).
‣ 71 clinical cases covering deficiency, toxicity, and dysregulation
‣ 41 mechanism-chain pathways, each with a clinical pearl
‣ Drug-induced deficiencies taught as causal chains: metformin and B12 in long-term diabetics, phenytoin and folate in seizure patients, TMP-SMX and folate on PCP prophylaxis, and more. Includes a searchable drug-nutrient interaction index for fast lookup.
‣ Macronutrient metabolism aligned with current Step 2 emphasis: gluconeogenesis, insulin signaling, β-oxidation, ketogenesis, NAFLD/SREBP, urea-cycle hyperammonemia
‣ Lifespan-specific pathways: periconception folate, maternal iodine, infant B12, neonatal vitamin K, congenital cretinism
‣ Food allergy vs intolerance discrimination (cow's milk protein allergy, celiac disease)
‣ Eating-disorder identification with DSM-5 criteria and refeeding-syndrome management protocol
‣ Nutrition label interpretation for chronic-disease counseling
‣ A competency dashboard tracking your progress against every JAMA 2024 nutrition competency the app teaches
FREE TIER
Vitamin B12 unlocked forever. Three cases (pernicious anaemia, nitrous-oxide-induced SACD, infant of vegan mother) and two pathways (MMA cycle, breastmilk-infant myelination) - enough to run the complete case → pathway → review loop and decide if Kinetics fits your study style.
ONE-TIME PURCHASE
One-time purchase. No subscription. Every future content update included.
BUILT BY DIAGNOSTIC STUDIOS
Also makers of MedDiagnosis (clinical case simulator) and PathoPlay (disease and drug mechanisms).
For educational use only. Not for clinical decision-making.
USMLE® is a registered trademark of the FSMB and NBME. Kinetics is independent and not affiliated with or endorsed by the USMLE program, FSMB, or NBME.
What's New in Version 2.0.0
NEW: JAMA 2024 nutrition competency dashboard - every case and pathway mapped to the framework the USMLE cites for the June 2026 nutrition update.
NEW: Drug-nutrient interaction search - typeahead reference for 18 indexed agents with mechanism, management, and worked-case links.
9 NEW CLINICAL CASES
• Wolff-Chaikoff iodine-induced hypothyroidism
• Pediatric lead poisoning vs iron-deficiency anaemia
• Cirrhosis multi-deficiency syndrome
• Anaemia of chronic disease vs IDA
• TMP-SMX prophylaxis pancytopenia
• Cow's milk protein allergy vs lactose intolerance
• Adult celiac disease with multi-deficiency
• Anorexia nervosa with refeeding-syndrome anticipation
• Hidden added sugars and nutrition-label literacy
4 NEW MECHANISM PATHWAYS
• Urea cycle (CPS-I, NAG, hyperammonemia)
• TCA cycle 5-cofactor stack at α-ketoglutarate dehydrogenase
• Phenytoin → folate (conjugase + CYP induction)
• Trimethoprim DHFR selectivity ladder
NEW MACRONUTRIENT AXIS
Amino-acid metabolism + urea-cycle nitrogen disposal - anchoring the new urea cycle pathway and acquired hyperammonemia content.
Seller
Name
Helena Kaso
Information
Developer
Categories
Version
2.0.0
Size
53.7 MB
Game Center
No
VPP Device Licensing
Yes
Rating
Rated 12+ for the following:
Infrequent/Mild Medical/Treatment Information
Compatibility
iOS 15.1 or later
Devices
iPhone 5s, iPhone 6, iPhone 6 Plus, iPhone 6s, iPhone 6s Plus, iPhone SE, iPhone 7, iPhone 7 Plus, iPhone 8, iPhone 8 Plus, iPhone X, iPhone XR, iPhone XS, iPhone XS Max, iPhone 11, iPhone 11 Pro, iPhone 11 Pro Max, iPhone SE (2nd generation), iPhone 12, iPhone 12 Pro, iPhone 12 Pro Max, iPhone 12 mini, iPhone 13, iPhone 13 Pro, iPhone 13 Pro Max, iPhone 13 mini, iPhone SE (3rd generation), iPhone 14, iPhone 14 Plus, iPhone 14 Pro, iPhone 14 Pro Max, iPhone 15, iPhone 15 Plus, iPhone 15 Pro, iPhone 15 Pro Max, iPhone 16, iPhone 16 Plus, iPhone 16 Pro, iPhone 16 Pro Max, iPhone 16e, iPhone 17, iPhone 17 Pro, iPhone 17 Pro Max, iPhone Air, iPhone 17e, iPad (5th Generation) Wi-Fi, iPad (5th Generation) Wi-Fi + Cellular, iPad (6th generation) Wi-Fi, iPad (6th generation) Wi-Fi + Cellular, iPad Pro, iPad Pro (Cellular), iPad Pro (9.7-inch), iPad Pro (9.7-inch) (Cellular), iPad Pro 12.9-inch (2nd generation), iPad Pro 12.9-inch (2nd generation) Wi-Fi + Cellular, iPad Pro (10.5-inch), iPad Pro (10.5-inch) Wi-Fi + Cellular, iPad Pro (11-inch), iPad Pro (11-inch) Wi-Fi + Cellular, iPad Pro 12.9-inch (3rd generation), iPad Pro 12.9-inch (3rd generation) Wi-Fi + Cellular, iPad Air, iPad Air (Cellular), iPad Air 2, iPad Air 2 (Cellular), iPad Air (3rd generation), iPad Air (3rd generation) Wi-Fi + Cellular, iPad mini Retina, iPad mini Retina (Cellular), iPad mini 3, iPad mini 3 (Cellular), iPad mini 4, iPad mini 4 (Cellular), iPad mini (5th Generation), iPad mini (5th Generation) Wi-Fi + Cellular, iPad (7th generation) Wi-Fi + Cellular, iPad Pro 11-inch (2nd generation), iPad Pro 11-inch (2nd generation) Wi-Fi + Cellular, iPad Pro 12.9-inch (4th generation), iPad Pro 12.9-inch (4th generation) Wi-Fi + Cellular, iPad Air (4th Generation) (Wi-Fi), iPad Air (4th Generation) (Wi-Fi + Cellular), iPad (8th generation) Wi-Fi, iPad (8th generation) Wi-Fi + Cellular, iPad Pro 11-inch (3rd generation), iPad Pro 11-inch (3rd generation) Wi-Fi + Cellular, iPad Pro 12.9-inch (5th Generation), iPad Pro 12.9-inch (5th Generation) Wi-Fi + Cellular, iPad (9th Generation), iPad (9th Generation) Wi-Fi + Cellular, iPad mini (6th Generation), iPad mini (6th Generation) Wi-Fi + Cellular, iPad Air (5th generation), iPad Air (5th generation) Wi-Fi + Cellular, iPad Pro 11-inch (4th generation), iPad Pro 11-inch (4th generation) Wi-Fi + Cellular, iPad Pro 12.9-inch (6th generation), iPad Pro 12.9-inch (6th generation) Wi-Fi + Cellular, iPad (10th generation), iPad (10th generation) Wi-Fi + Cellular, iPad Air 11-inch (M2) Wi-Fi, iPad Air 13-inch (M2) Wi-Fi, iPad Air 13-inch (M2) Wi-Fi + Cellular, iPad Pro 11-inch (M4) Wi-Fi, iPad Pro 11-inch (M4) Wi-Fi + Cellular, iPad Pro 13-inch (M4) Wi-Fi, iPad Pro 13-inch (M4) Wi-Fi + Cellular, iPad mini (A17 Pro) Wi-Fi, iPad mini (A17 Pro) Wi-Fi + Cellular, iPad (A16) Wi-Fi, iPad (A16) Wi-Fi + Cellular, iPad Air 11-inch (M3) Wi-Fi, iPad Air 11-inch (M3) Wi-Fi + Cellular, iPad Air 13-inch (M3) Wi-Fi, iPad Air 13-inch (M3) Wi-Fi + Cellular, iPad Pro 11-inch (M5) Wi-Fi, iPad Pro 11-inch (M5) Wi-Fi + Cellular, iPad Pro 13-inch (M5) Wi-Fi, iPad Pro 13-inch (M5) Wi-Fi + Cellular, iPad Air11M4, iPad Air11M4Cellular, iPad Air13M4, iPad Air13M4Cellular, iPod touch (6th Generation), iPod touch (7th generation)
Languages
English
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