From the high seas of the Indian Ocean to the dark jungles of Southeast Asia, from the canals of Venice to the crypts of ancient kings, SIGMA Force must piece together a mystery that, unless solved, will end all life on our planet...

But even this challenge may prove too large for SIGMA Force alone. With a worldwide pandemic growing, Painter Crowe and Commander Gray Pierce turn to their deadliest adversaries for help, teaming up with a diabolical foe that has thwarted them in the past. But can the enemy be trusted even now? Or will they prove to be another Judas...?