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The Next Experiment

The Next Experiment

Released: 2024-11-27
© The Next Experiment
The Next Experiment - QR Code
5 Episodes
Audio
Listen on Apple Podcasts
5 Episodes
Audio
Listen on Apple Podcasts
Released: 2024-11-27
© The Next Experiment
Most Recent Episode
What the Past Teaches Us About Future Experiments

What the Past Teaches Us About Future Experiments

Time: 25:47
To explore what the future of multidimensional experiments might look like, we decided to look back.
In this episode, we explored how different multi-dimensional (aka Design of Experiments, or DOE) methods have come about to date. 
Then, we pondered how these different methods, together with tech and software innovations, have brought both opportunities to scale multidimensional experimentation, and exciting questions on the best way to go about it.
Conversation highlights
00:00 - Introduction
01:04 - The question mark around automation: what to do with 1000+ runs  
10:15 - History of multidimensional (Design of Experiments / DOE) methods to date:
10:58 - Era 1: Factorial designs came about, and benefited agriculture
15:12 - Era 2: Response surface methods emerged in process industries
18:17 - Era 3: Software packages helped design the “optimal” experiment  
21:29 - “DOE 4.0”: Bayesian optimization, and the pros and cons for biology
Episode ID: 1000678376044
GUID: d83428d0-f3a3-493a-9c63-270d95fc8cac
Release Date: 27/11/2024, 07:30:00

Description

It's vital that we make progress in biology. Yet today, understanding complex living systems is hard.
But does it have to be?
We're Markus and Phil, a biologist and a statistician.
We created this podcast for anyone who believes that there might be a better way. Together, we'll discuss the best experiments to cut through biological complexity.
Join us to explore the shape of the next experiment.

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